Phosphatidylinositol-transfer protein and its homologues in yeast.

نویسندگان

  • P Griac
  • R Holic
  • D Tahotna
چکیده

Yeast Sec14p acts as a phosphatidylinositol/phosphatidylcholine-transfer protein in vitro. In vivo, it is essential in promoting Golgi secretory function. Products of five genes named SFH1-SFH5 (Sec Fourteen Homologues 1-5) exhibit significant sequence homology to Sec14p and together they form the Sec14p family of lipid-transfer proteins. It is a diverse group of proteins with distinct subcellular localizations and varied physiological functions related to lipid metabolism and membrane trafficking.

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عنوان ژورنال:
  • Biochemical Society transactions

دوره 34 Pt 3  شماره 

صفحات  -

تاریخ انتشار 2006